Products

Viscoadaptive Peptide Matrix for Fast, Protected Closure
Granulation in Just Two Weekly Doses
Chronic DFU, VLU, and post-surgical wounds often stall when dead space, biofilm, and poor perfusion persist. In a prospective case-series of five complex wounds, surgeons achieved complete closure after only two weekly applications of G4Derm Plus® and reported no device-related adverse events.¹ The visco-adaptive matrix conformed to tunnels and undermines, eliminating dead space, while multispectral imaging in a separate cohort showed a > 65 % drop in ischemic zone within 14 days, mirroring rapid granulation.
Visco-adaptive Scaffold that Shields - and Rebuilds
Unlike biologic grafts that merely cover the surface, G4Derm Plus delivers a peptide-engineered scaffold that flows into hard-to-reach areas, self-assembles into an ECM-like matrix, and provides broad-spectrum antibacterial protection (ā„ 6-log kill of MRSA and Gram-negative isolates in vitro). The cationic peptides disrupt biofilm while arginine, lysine, and proline fuel collagen synthesis, allowing clinicians to see ā„ 60 % area reduction-or full closure-after two to five weekly doses in uncontrolled reports.¹³ Ready-to-use pre-filled syringes keep OR prep to seconds, making āshield and rebuildā a single-step procedure.

Key Features
G4Derm PlusĀ® - Flowable peptide matrix engineered for rapid, protected wound closure.
Visco-adaptive Matrix Conforms & Fills
Self-assembles into deep tunnels and undermines, eliminating dead space for uniform contact.
Broad-Spectrum Antibacterial Barrier
In vitro tests show ā„ 6-log kill of MRSA and Gram-negative isolates, helping prevent biofilm rebound.
Rapid Perfusion & Granulation Boost
Multispectral NIRS study recorded a > 65 % drop in ischemic zone within 14 days, paralleling visible granulation.

